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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX1B
All Species:
27.27
Human Site:
S248
Identified Species:
46.15
UniProt:
P61266
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61266
NP_443106.1
288
33245
S248
D
Y
V
E
R
A
V
S
D
T
K
K
A
V
K
Chimpanzee
Pan troglodytes
XP_001146812
288
32492
S249
D
Y
V
E
R
A
V
S
D
T
K
K
A
V
K
Rhesus Macaque
Macaca mulatta
XP_001103901
336
38070
S296
D
Y
V
E
R
A
V
S
D
T
K
K
A
V
K
Dog
Lupus familis
XP_547038
348
39606
S256
D
Y
V
E
R
A
V
S
D
T
K
K
A
V
K
Cat
Felis silvestris
Mouse
Mus musculus
O35526
288
33036
S249
D
Y
V
E
R
A
V
S
D
T
K
K
A
V
K
Rat
Rattus norvegicus
P32851
288
33049
S249
D
Y
V
E
R
A
V
S
D
T
K
K
A
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990405
282
32496
F242
D
Y
V
E
P
V
V
F
V
T
K
S
A
V
M
Frog
Xenopus laevis
NP_001086322
286
32704
A247
G
F
V
E
R
A
V
A
D
T
K
K
A
V
K
Zebra Danio
Brachydanio rerio
NP_571598
288
33347
S248
D
Y
V
E
R
A
V
S
D
T
K
K
A
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
Q252
D
Y
V
Q
T
A
T
Q
D
T
K
K
A
L
K
Honey Bee
Apis mellifera
XP_393760
291
33455
Q253
D
Y
V
Q
T
A
T
Q
D
T
K
K
A
L
K
Nematode Worm
Caenorhab. elegans
O16000
291
33234
A250
E
F
V
D
R
A
V
A
D
T
K
K
A
V
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZQZ8
305
34465
D263
S
F
V
M
R
G
T
D
Q
L
H
G
A
K
V
Baker's Yeast
Sacchar. cerevisiae
P39926
295
33715
G251
Q
D
V
E
Q
G
V
G
H
T
N
K
A
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.7
85.1
75.5
N.A.
84
83.6
N.A.
N.A.
84.7
62.5
96.8
N.A.
68.7
66.3
59.1
N.A.
Protein Similarity:
100
88.1
85.7
78.1
N.A.
94.4
94
N.A.
N.A.
87.5
84
98.2
N.A.
82.1
79
78.3
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
60
80
100
N.A.
66.6
66.6
66.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
60
93.3
100
N.A.
80
80
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.9
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.8
49.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
79
0
15
0
0
0
0
100
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
72
8
0
8
0
0
0
8
79
0
0
0
0
0
0
% D
% Glu:
8
0
0
72
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
22
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
15
0
8
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
86
86
0
8
79
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
0
0
0
15
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
15
8
0
0
15
8
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
72
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
50
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
15
0
22
0
0
93
0
0
0
0
0
% T
% Val:
0
0
100
0
0
8
79
0
8
0
0
0
0
79
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
72
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _